New microscope designed to reveal the function of individual genes in the brain
Many diseases also have a genetic component. For example, gene mutations can lead to the development of cancer or psychiatric disorders such as schizophrenia, depression or autism. Most of these diseases seem to be caused not by a single mutation but are rather the result of the interplay of dozens, maybe even hundreds of altered gene functions. It would therefore be of great benefit for the investigation, diagnosis and therapy of these illnesses, to identify the affected genes and monitor their activity in the brain of the living organism.
An interdisciplinary team around Herwig Baier from the Max Planck Institute of Neurobiology, Attila Sik from the University of Birmingham, Miklós Veres from the Wigner Institute and the microscope developers at Femtonics Ltd. aim to develop such a method. (more)