Student Publications

Brüggenthies, J.B., Fiore, A., Russier, M., Bitsina, C., Brötzmann, J., Kordes, S., Menninger, S., Wolf, A., Conti, E., Eickhoff, J.E., and Murray, P.J. (2022). A cell-based chemical-genetic screen for amino acid stress response inhibitors reveals torins reverse stress kinase GCN2 signaling. J Biol Chem, 102629.

Sethi, A., Wei, H., Mishra, N., Segos, I., Lambie, E.J., Zanin, E., and Conradt, B. (2022). A caspase-RhoGEF axis contributes to the cell size threshold for apoptotic death in developing Caenorhabditis elegans. PLoS Biol 20, e3001786.

Martín Caballero, L., Capella, M., Barrales, R.R., Dobrev, N., van Emden, T., Hirano, Y., Suma Sreechakram, V.N., Fischer-Burkart, S., Kinugasa, Y., Nevers, A., Rougemaille, M., Sinning, I., Fischer, T., Hiraoka, Y., and Braun, S. (2022). The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery. Nat Struct Mol Biol 29, 910-921.

Huisjes, N.M., Retzer, T.M., Scherr, M.J., Agarwal, R., Rajappa, L., Safaric, B., Minnen, A., and Duderstadt, K.E. (2022). Mars, a molecule archive suite for reproducible analysis and reporting of single-molecule properties from bioimages. Elife 11.

Güner, G., Aßfalg, M., Zhao, K., Dreyer, T., Lahiri, S., Lo, Y., Slivinschi, B.I., Imhof, A., Jocher, G., Strohm, L., Behrends, C., Langosch, D., Bronger, H., Nimsky, C., Bartsch, J.W., Riddell, S.R., Steiner, H., and Lichtenthaler, S.F. (2022). Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ-secretase activity. EMBO Mol Med, e16084.

Blessing, C., Apelt, K., van den Heuvel, D., Gonzalez-Leal, C., Rother, M.B., van der Woude, M., González-Prieto, R., Yifrach, A., Parnas, A., Shah, R.G., Kuo, T.T., Boer, D.E.C., Cai, J., Kragten, A., Kim, H.S., Schärer, O.D., Vertegaal, A.C.O., Shah, G.M., Adar, S., Lans, H., van Attikum, H., Ladurner, A.G., and Luijsterburg, M.S. (2022). XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair. Nat Commun 13, 4762.

Behrens, A., and Nedialkova, D.D. (2022). Experimental and computational workflow for the analysis of tRNA pools from eukaryotic cells by mim-tRNAseq. STAR Protoc 3, 101579.

Bergant, V., Yamada, S., Grass, V., Tsukamoto, Y., Lavacca, T., Krey, K., Mühlhofer, M.T., Wittmann, S., Ensser, A., Herrmann, A., Vom Hemdt, A., Tomita, Y., Matsuyama, S., Hirokawa, T., Huang, Y., Piras, A., Jakwerth, C.A., Oelsner, M., Thieme, S., Graf, A., Krebs, S., Blum, H., Kümmerer, B.M., Stukalov, A., Schmidt-Weber, C.B., Igarashi, M., Gramberg, T., Pichlmair, A., and Kato, H. (2022). Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases. EMBO J, e111608.

Emslander, Q., Vogele, K., Braun, P., Stender, J., Willy, C., Joppich, M., Hammerl, J.A., Abele, M., Meng, C., Pichlmair, A., Ludwig, C., Bugert, J.J., Simmel, F.C., and Westmeyer, G.G. (2022). Cell-free production of personalized therapeutic phages targeting multidrug-resistant bacteria. Cell Chem Biol, Online ahead of print.

Riera-Tur, I., Schäfer, T., Hornburg, D., Mishra, A., da Silva Padilha, M., Fernández-Mosquera, L., Feigenbutz, D., Auer, P., Mann, M., Baumeister, W., Klein, R., Meissner, F., Raimundo, N., Fernández-Busnadiego, R., and Dudanova, I. (2022). Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity. Life Sci Alliance 5.

Oz, T., Mengoli, V., Rojas, J., Jonak, K., Braun, M., Zagoriy, I., and Zachariae, W. (2022). The Spo13/Meikin pathway confines the onset of gamete differentiation to meiosis II in yeast. EMBO J 41, e109446.

Brunner, A.-D., Thielert, M., Vasilopoulou, C., Ammar, C., Coscia, F., Mund, A., Horning, O.B., Bache, N., Apalategui, A., Lubeck, M., Raether, O., Park, M.A., Richter, S., Fischer, D.S., Theis, F.J., Meier, F., and Mann, M. (2022). Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation. Mol Syst Biol 18, e10798.

Reifschneider, A., Robinson, S., van Lengerich, B., Gnörich, J., Logan, T., Heindl, S., Vogt, M.A., Weidinger, E., Riedl, L., Wind, K., Zatcepin, A., Pesämaa, I., Haberl, S., Nuscher, B., Kleinberger, G., Klimmt, J., Götzl, J.K., Liesz, A., Bürger, K., Brendel, M., Levin, J., Diehl-Schmid, J., Suh, J., Di Paolo, G., Lewcock, J.W., Monroe, K.M., Paquet, D., Capell, A., and Haass, C. (2022). Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency. EMBO J 41, e109108.

Scherr, M.J., Wahab, S.A., Remus, D., and Duderstadt, K.E. (2022). Mobile origin-licensing factors confer resistance to conflicts with RNA polymerase. Cell Rep 38, 110531.

Schmacke, N.A., and Hornung, V. (2022). Homing in on gasdermins: How fungi regulate cell death. Proc Natl Acad Sci U S A 119, e2201192119.

Hamzeiy, H., Ferretti, D., Robles, M.S., and Cox, J. (2022). Perseus plugin "Metis" for metabolic-pathway-centered quantitative multi-omics data analysis for static and time-series experimental designs. Cell Rep Methods 2, 100198.

Brandstetter, K., Zülske, T., Ragoczy, T., Hörl, D., Guirao-Ortiz, M., Steinek, C., Barnes, T., Stumberger, G., Schwach, J., Haugen, E., Rynes, E., Korber, P., Stamatoyannopoulos, J.A., Leonhardt, H., Wedemann, G., and Harz, H. (2022). Differences in nanoscale organization of regulatory active and inactive human chromatin. Biophys J 121, 977-990.

Weickert, P., and Stingele, J. (2022). DNA-Protein Crosslinks and Their Resolution. Annu Rev Biochem.

Hees, J.T., and Harbauer, A.B. (2022). Live-Cell Imaging of RNA Transport in Axons of Cultured Primary Neurons. Methods Mol Biol 2431, 225-237.

Jocher, G., Grass, V., Tschirner, S.K., Riepler, L., Breimann, S., Kaya, T., Oelsner, M., Hamad, M.S., Hofmann, L.I., Blobel, C.P., Schmidt-Weber, C.B., Gokce, O., Jakwerth, C.A., Trimpert, J., Kimpel, J., Pichlmair, A., and Lichtenthaler, S.F. (2022). ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion. EMBO reports n/a, e54305.

Schneider, M.F., Müller, V., Müller, S.A., Lichtenthaler, S.F., Becker, P.B., and Scheuermann, J.C. (2022). LncRNA RUS shapes the gene expression program towards neurogenesis. Life Sci Alliance 5.

O'Neill, A.C., Uzbas, F., Antognolli, G., Merino, F., Draganova, K., Jäck, A., Zhang, S., Pedini, G., Schessner, J.P., Cramer, K., Schepers, A., Metzger, F., Esgleas, M., Smialowski, P., Guerrini, R., Falk, S., Feederle, R., Freytag, S., Wang, Z., Bahlo, M., Jungmann, R., Bagni, C., Borner, G.H.H., Robertson, S.P., Hauck, S.M., and Götz, M. (2022). Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity. Science 376, eabf9088.

Dequeker, B.J.H., Scherr, M.J., Brandão, H.B., Gassler, J., Powell, S., Gaspar, I., Flyamer, I.M., Lalic, A., Tang, W., Stocsits, R., Davidson, I.F., Peters, J.M., Duderstadt, K.E., Mirny, L.A., and Tachibana, K. (2022). MCM complexes are barriers that restrict cohesin-mediated loop extrusion. Nature, 606, 197-203.

Groschner, L.N., Malis, J.G., Zuidinga, B., and Borst, A. (2022). A biophysical account of multiplication by a single neuron. Nature 603, 119-123.

Qin, W., Steinek, C., Kolobynina, K., Forné, I., Imhof, A., Cardoso, M.C., and Leonhardt, H. (2022). Probing protein ubiquitination in live cells. Nucleic Acids Res.

Ober, M.F., Baptist, A., Wassermann, L., Heuer-Jungemann, A., and Nickel, B. (2022). In situ small-angle X-ray scattering reveals strong condensation of DNA origami during silicification. Nat Commun 13, 5668.

Wang, Z., Fan, R., Russo, A., Cernilogar, F.M., Nuber, A., Schirge, S., Shcherbakova, I., Dzhilyanova, I., Ugur, E., Anton, T., Richter, L., Leonhardt, H., Lickert, H., and Schotta, G. (2022). Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm. Nat Commun 13, 5447.

Bieber, A., Capitanio, C., Erdmann, P.S., Fiedler, F., Beck, F., Lee, C.W., Li, D., Hummer, G., Schulman, B.A., Baumeister, W., and Wilfling, F. (2022). In situ structural analysis reveals membrane shape transitions during autophagosome formation. Proc Natl Acad Sci U S A 119, e2209823119.

Stolz, P., Mantero, A.S., Tvardovskiy, A., Ugur, E., Wange, L.E., Mulholland, C.B., Cheng, Y., Wierer, M., Enard, W., Schneider, R., Bartke, T., Leonhardt, H., Elsässer, S.J., and Bultmann, S. (2022). TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation. Nucleic Acids Res 50, 8491-8511.

Gut, F., Käshammer, L., Lammens, K., Bartho, J.D., Boggusch, A.M., van de Logt, E., Kessler, B., and Hopfner, K.P. (2022). Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50. Mol Cell.

Hopf, L.V.M., Baek, K., Klügel, M., von Gronau, S., Xiong, Y., and Schulman, B.A. (2022). Structure of CRL7(FBXW8) reveals coupling with CUL1-RBX1/ROC1 for multi-cullin-RING E3-catalyzed ubiquitin ligation. Nat Struct Mol Biol, 29, 854-862.

Filipović, D., Novak, B., Xiao, J., Yan, Y., Yeoh, K., and Turck, C.W. (2022). Chronic fluoxetine treatment of socially isolated rats modulates prefrontal cortex proteome. Neuroscience, 501, 52-71.

Mund, A., Coscia, F., Kriston, A., Hollandi, R., Kovács, F., Brunner, A.D., Migh, E., Schweizer, L., Santos, A., Bzorek, M., Naimy, S., Rahbek-Gjerdrum, L.M., Dyring-Andersen, B., Bulkescher, J., Lukas, C., Eckert, M.A., Lengyel, E., Gnann, C., Lundberg, E., Horvath, P., and Mann, M. (2022). Deep Visual Proteomics defines single-cell identity and heterogeneity. Nat Biotechnol 40, 1231-1240.

Skowronek, P., Thielert, M., Voytik, E., Tanzer, M.C., Hansen, F.M., Willems, S., Karayel, Ö., Brunner, A.D., Meier, F., and Mann, M. (2022). Rapid and in-depth coverage of the (phospho-)proteome with deep libraries and optimal window design for dia-PASEF. Mol Cell Proteomics, 100279.

Mund, A., Brunner, A.D., and Mann, M. (2022). Unbiased spatial proteomics with single-cell resolution in tissues. Mol Cell 82, 2335-2349.

Karayel, O., Virreira Winter, S., Padmanabhan, S., Kuras, Y.I., Vu, D.T., Tuncali, I., Merchant, K., Wills, A.M., Scherzer, C.R., and Mann, M. (2022). Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson's disease. Cell Rep Med 3, 100661.

Kappel, J.M., Förster, D., Slangewal, K., Shainer, I., Svara, F., Donovan, J.C., Sherman, S., Januszewski, M., Baier, H., and Larsch, J. (2022). Visual recognition of social signals by a tectothalamic neural circuit. Nature 608, 146-152.

Stolz, P., Mantero, A.S., Tvardovskiy, A., Ugur, E., Wange, L.E., Mulholland, C.B., Cheng, Y., Wierer, M., Enard, W., Schneider, R., Bartke, T., Leonhardt, H., Elsässer, S.J., and Bultmann, S. (2022). TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation. Nucleic Acids Res, 50, 8491-8511.

Stazzoni, S., Böhmer, D.F.R., Hernichel, F., Özdemir, D., Pappa, A., Drexler, D., Bauernfried, S., Witte, G., Wagner, M., Veth, S., Hopfner, K.P., Hornung, V., König, L.M., and Carell, T. (2022). Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists. Angew Chem Int Ed Engl, 61, e202207175.

Robinson, K.S., Toh, G.A., Rozario, P., Chua, R., Bauernfried, S., Sun, Z., Firdaus, M.J., Bayat, S., Nadkarni, R., Poh, Z.S., Tham, K.C., Harapas, C.R., Lim, C.K., Chu, W., Tay, C.W.S., Tan, K.Y., Zhao, T., Bonnard, C., Sobota, R., Connolly, J.E., Common, J., Masters, S.L., Chen, K.W., Ho, L., Wu, B., Hornung, V., and Zhong, F.L. (2022). ZAKα-driven ribotoxic stress response activates the human NLRP1 inflammasome. Science 377, 328-335.

Liu, H., Bergant, V., Frishman, G., Ruepp, A., Pichlmair, A., Vincendeau, M., and Frishman, D. (2022). Influenza A Virus Infection Reactivates Human Endogenous Retroviruses Associated with Modulation of Antiviral Immunity. Viruses 14.

Khateb, H., Sørensen, R.S., Cramer, K., Eklund, A.S., Kjems, J., Meyer, R.L., Jungmann, R., and Sutherland, D.S. (2022). The Role of Nanoscale Distribution of Fibronectin in the Adhesion of Staphylococcus aureus Studied by Protein Patterning and DNA-PAINT. ACS Nano 16, 10392-10403.

Strohm, L., Hu, Z., Suk, Y., Rühmkorf, A., Sternburg, E., Gattringer, V., Riemenschneider, H., Berutti, R., Graf, E., Weishaupt, J.H., Brill, M.S., Harbauer, A.B., Dormann, D., Dengjel, J., Edbauer, D., and Behrends, C. (2022). Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants. Life Sci Alliance 5.

Schaller, T., Märkl, B., Claus, R., Sholl, L., Hornick, J.L., Giannetti, M.P., Schweizer, L., Mann, M., and Castells, M. (2022). Mast cells in lung damage of COVID-19 autopsies: A descriptive study. Allergy 77, 2237-2239.

Tacke, S., Erdmann, P., Wang, Z., Klumpe, S., Grange, M., Plitzko, J., and Raunser, S. (2021). A streamlined workflow for automated cryo focused ion beam milling. J Struct Biol 213, 107743.

Alonso-Nocelo, M., Ruiz-Cañas, L., Sancho, P., Görgülü, K., Alcalá, S., Pedrero, C., Vallespinos, M., López-Gil, J.C., Ochando, M., García-García, E., David Trabulo, S.M., Martinelli, P., Sánchez-Tomero, P., Sánchez-Palomo, C., Gonzalez-Santamaría, P., Yuste, L., Wörmann, S.M., Kabacaoğlu, D., Earl, J., Martin, A., Salvador, F., Valle, S., Martin-Hijano, L., Carrato, A., Erkan, M., García-Bermejo, L., Hermann, P.C., Algül, H., Moreno-Bueno, G., Heeschen, C., Portillo, F., Cano, A., and Sainz, B., Jr. (2022). Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma. Gut, Online ahead of print.

Safaric, B., Chacin, E., Scherr, M.J., Rajappa, L., Gebhardt, C., Kurat, C.F., Cordes, T., and Duderstadt, K.E. (2022). The fork protection complex recruits FACT to reorganize nucleosomes during replication. Nucleic Acids Res 50, 1317-1334.

Dichtl, S., Sanin, D.E., Koss, C.K., Willenborg, S., Petzold, A., Tanzer, M.C., Dahl, A., Kabat, A.M., Lindenthal, L., Zeitler, L., Satzinger, S., Strasser, A., Mann, M., Roers, A., Eming, S.A., El Kasmi, K.C., Pearce, E.J., and Murray, P.J. (2022). Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF. Life Sci Alliance 5.

Fiore, A., Zeitler, L., Russier, M., Groß, A., Hiller, M.K., Parker, J.L., Stier, L., Köcher, T., Newstead, S., and Murray, P.J. (2022). Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling. Mol Cell 82, 920-932.e927.

Albanese, M., Ruhle, A., Mittermaier, J., Mejías-Pérez, E., Gapp, M., Linder, A., Schmacke, N.A., Hofmann, K., Hennrich, A.A., Levy, D.N., Humpe, A., Conzelmann, K.K., Hornung, V., Fackler, O.T., and Keppler, O.T. (2022). Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4(+) T cells allows complex functional analyses. Nat Methods 19, 81-89.

Wratil, P.R., Schmacke, N.A., Osterman, A., Weinberger, T., Rech, J., Karakoc, B., Zeilberger, M., Steffen, J., Mueller, T.T., Spaeth, P.M., Stern, M., Albanese, M., Thun, H., Reinbold, J., Sandmeyer, B., Kressirer, P., Grabein, B., Falkai, P., Adorjan, K., Hornung, V., Kaderali, L., Klein, M., and Keppler, O.T. (2022). In-depth profiling of COVID-19 risk factors and preventive measures in healthcare workers. Infection 50, 381-394.

Schmidt, M., Kluge, F., Sandmeir, F., Kühn, U., Schäfer, P., Tüting, C., Ihling, C., Conti, E., and Wahle, E. (2022). Reconstitution of 3' end processing of mammalian pre-mRNA reveals a central role of RBBP6. Genes Dev 36, 195-209.

Bludau, I., Willems, S., Zeng, W.F., Strauss, M.T., Hansen, F.M., Tanzer, M.C., Karayel, O., Schulman, B.A., and Mann, M. (2022). The structural context of posttranslational modifications at a proteome-wide scale. PLoS Biol 20, e3001636.

Falcomatà, C., Bärthel, S., Widholz, S.A., Schneeweis, C., Montero, J.J., Toska, A., Mir, J., Kaltenbacher, T., Heetmeyer, J., Swietlik, J.J., Cheng, J.Y., Teodorescu, B., Reichert, O., Schmitt, C., Grabichler, K., Coluccio, A., Boniolo, F., Veltkamp, C., Zukowska, M., Vargas, A.A., Paik, W.H., Jesinghaus, M., Steiger, K., Maresch, R., Öllinger, R., Ammon, T., Baranov, O., Robles, M.S., Rechenberger, J., Kuster, B., Meissner, F., Reichert, M., Flossdorf, M., Rad, R., Schmidt-Supprian, M., Schneider, G., and Saur, D. (2022). Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment. Nat Cancer 3, 318-336.

Malik, M.N.H., Waqas, S.F., Zeitvogel, J., Cheng, J., Geffers, R., Gouda, Z.A., Elsaman, A.M., Radwan, A.R., Schefzyk, M., Braubach, P., Auber, B., Olmer, R., Müsken, M., Roesner, L.M., Gerold, G., Schuchardt, S., Merkert, S., Martin, U., Meissner, F., Werfel, T., and Pessler, F. (2022). Congenital deficiency reveals critical role of ISG15 in skin homeostasis. J Clin Invest 132.

Harbauer, A.B., Hees, J.T., Wanderoy, S., Segura, I., Gibbs, W., Cheng, Y., Ordonez, M., Cai, Z., Cartoni, R., Ashrafi, G., Wang, C., Perocchi, F., He, Z., and Schwarz, T.L. (2022). Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy. Neuron 110, 1516-1531.e1519.

Jones, A.N., Tikhaia, E., Mourão, A., and Sattler, M. (2022). Structural effects of m6A modification of the Xist A-repeat AUCG tetraloop and its recognition by YTHDC1. Nucleic Acids Res 50, 2350-2362.

Riemenschneider, H., Guo, Q., Bader, J., Frottin, F., Farny, D., Kleinberger, G., Haass, C., Mann, M., Hartl, F.U., Baumeister, W., Hipp, M.S., Meissner, F., Fernández-Busnadiego, R., and Edbauer, D. (2022). Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons. EMBO Rep, e53890.

Schaller, T., Märkl, B., Claus, R., Sholl, L., Hornick, J.L., Giannetti, M.P., Schweizer, L., Mann, M., and Castells, M. (2022). Mast Cells in Lung Damage of COVID-19 Autopsies: a descriptive study. Allergy.

Weckbach, L.T., Schweizer, L., Kraechan, A., Bieber, S., Ishikawa-Ankerhold, H., Hausleiter, J., Massberg, S., Straub, T., Klingel, K., Grabmaier, U., Zwiebel, M., Mann, M., and Schulz, C. (2022). Association of Complement and MAPK Activation With SARS-CoV-2-Associated Myocardial Inflammation. JAMA Cardiol 7, 286-297.

Mund, A., Coscia, F., Kriston, A., Hollandi, R., Kovács, F., Brunner, A.D., Migh, E., Schweizer, L., Santos, A., Bzorek, M., Naimy, S., Rahbek-Gjerdrum, L.M., Dyring-Andersen, B., Bulkescher, J., Lukas, C., Eckert, M.A., Lengyel, E., Gnann, C., Lundberg, E., Horvath, P., and Mann, M. (2022). Deep Visual Proteomics defines single-cell identity and heterogeneity. Nat Biotechnol, Online ahead of print.

Qiao, S., Lee, C.W., Sherpa, D., Chrustowicz, J., Cheng, J., Duennebacke, M., Steigenberger, B., Karayel, O., Vu, D.T., von Gronau, S., Mann, M., Wilfling, F., and Schulman, B.A. (2022). Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation. Nat Commun 13, 3041.

Langlois, C.R., Beier, V., Karayel, O., Chrustowicz, J., Sherpa, D., Mann, M., and Schulman, B.A. (2022). A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters. EMBO Rep 23, e53835.

Lopez, J.P., Lücken, M.D., Brivio, E., Karamihalev, S., Kos, A., De Donno, C., Benjamin, A., Yang, H., Dick, A.L.W., Stoffel, R., Flachskamm, C., Ressle, A., Roeh, S., Huettl, R.E., Parl, A., Eggert, C., Novak, B., Yan, Y., Yeoh, K., Holzapfel, M., Hauger, B., Harbich, D., Schmid, B., Di Giaimo, R., Turck, C.W., Schmidt, M.V., Deussing, J.M., Eder, M., Dine, J., Theis, F.J., and Chen, A. (2022). Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2. Neuron, Online ahead of print.

Lersch, R., Jannadi, R., Grosse, L., Wagner, M., Schneider, M.F., von Stülpnagel, C., Heinen, F., Potschka, H., and Borggraefe, I. (2022). Targeted Molecular Strategies for Genetic Neurodevelopmental Disorders: Emerging Lessons from Dravet Syndrome. Neuroscientist, 10738584221088244.

 

Klein, A.S., Dolensek, N., Weiand, C., and Gogolla, N. (2021). Fear balance is maintained by bodily feedback to the insular cortex in mice. Science 374, 1010-1015.

Bauernfried, S., Scherr, M.J., Pichlmair, A., Duderstadt, K.E., and Hornung, V. (2021). Human NLRP1 is a sensor for double-stranded RNA. Science 371.

Bauernfried, S., and Hornung, V. (2021). DPP9 restrains NLRP1 activation. Nat Struct Mol Biol 28, 333-336.

Klein, A.S., and Gogolla, N. (2021). How mice feel each other's pain or fear. Science 371, 122-123.

Amaro, D., Ferreiro, D.N., Grothe, B., and Pecka, M. (2021). Source identity shapes spatial preference in primary auditory cortex during active navigation. Curr Biol 31, 3875-3883.e3875.

Kober-Hasslacher, M., Oh-Strauss, H., Kumar, D., Soberon, V., Diehl, C., Lech, M., Engleitner, T., Katab, E., Fernandez-Saiz, V., Piontek, G., Li, H., Menze, B., Ziegenhain, C., Enard, W., Rad, R., Bottcher, J.P., Anders, H.J., Rudelius, M., and Schmidt-Supprian, M. (2020). c-Rel gain in B cells drives germinal center reactions and autoantibody production. J Clin Invest 130, 3270-3286.

Üçpunar, H.K., and Grunwald Kadow, I.C. (2021). Flies Avoid Current Atmospheric CO(2) Concentrations. Front Physiol 12, 646401.

Frauenstein, A., Ebner, S., Hansen, F.M., Sinha, A., Phulphagar, K., Swatek, K., Hornburg, D., Mann, M., and Meissner, F. (2021). Identification of covalent modifications regulating immune signaling complex composition and phenotype. Mol Syst Biol 17, e10125.

Mengoli, V., Jonak, K., Lyzak, O., Lamb, M., Lister, L.M., Lodge, C., Rojas, J., Zagoriy, I., Herbert, M., and Zachariae, W. (2021). Deprotection of centromeric cohesin at meiosis II requires APC/C activity but not kinetochore tension. EMBO J 40, e106812.

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